By Alexander Hintz, DVM
Tylvalosin is a newer -generation macrolide antibiotic present in both Aivlosin® 62.5% Water Soluble Granules (WSG) and Aivlosin 17% Type A Medicated Article.
Both products are labeled for the control of ileitis (Lawsonia intracellularis) and additionally, Aivlosin WSG is labeled for the control of Swine Respiratory Disease.
The warm, humid weather of the summer months brings a primary herd-health risk to the forefront for swine veterinarians and producers: ileitis. The familiar somewhat darker, loose stools in grow-finish hogs is an unwanted reminder to veterinarians that ileitis infection could be present. When signs of disease emerge, Aivlosin® WSG is an excellent choice for ileitis control in swine herds. Following administration, Tylvalosin is rapidly absorbed reaching peak blood levels in approximately two hours. Tylvalosin is metabolized to – 3 acetyltylosin (3-AT) – which also has antimicrobial activity. These attributes make Aivlosin® extremely efficacious in the control of ileitis in swine herds.
As well as providing excellent control of ileitis Aivlosin® WSG is also labelled for the control of swine respiratory disease (SRD) associated with major bacterial pathogens such as Pasteurella multocida, Bordetella bronchiseptica, Streptococcus suis, and Haemophilus parasuis.
Disease is non-discriminatory in swine herds, and producers may struggle with both respiratory disease and ileitis simultaneously at various stages of production. Aivlosin® is a judicious choice with its low therapeutic dose, its short treatment duration and with broad-spectrum activity against both specific respiratory and enteric pathogen.
The rapid absorption and excretion of tylavlosin gives the product an industry-leading zero-day slaughter withdrawal. Additionally, Aivlosin®, is very safe –no drug related adverse reactions were observed during target animal safety or clinical trials and there are no known adverse interactions between the use of Aivlosin® WSG and ionophores used in the feed (such as Skycis®).
With its broad-spectrum label, rapid absorption, and its zero-day slaughter withdrawal time, Aivlosin® WSG provides the veterinarian with an efficacious product and is a judicious antimicrobial choice for their clients’ swine herds.
CHOICES FOR WATER AND FEED MEDICATION
Aivlosin® Water Soluble Granules is labeled as a 5-day continuous treatment administered in the drinking water at 50 PPM tylvalosin,
Alternatively Aivlosin® 17% Type A Medicated Article is also approved for the control of ileitis at an inclusion rate of 42.5ppm in Type C feed and given continuously for 14-day period.
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Important Safety Information: Available under prescription only. AIVLOSIN® 62.5% Water soluble granules is indicated for the control of swine respiratory disease (SRD) associated with Bordetella bronchiseptica, Haemophilus parasuis, Pasteurella multocida and Streptococcus suis, or PPE associated with Lawsonia intracellularis, in groups of swine in a building experiencing an outbreak of either disease. For use only in drinking water of pigs. Not for use in lactating or pregnant females, or males and females intended for breeding. People with known hypersensitivity to tylvalosin tartrate should avoid contact with this product. When used in accordance with label directions, no withdrawal period is required before slaughter for human consumption.
The Important Safety information for premix is to be added.
® Aivlosin is a registered trademark from ECO Animal Health Ltd., London, United Kingdom; Skycis is a registered trademark of Eli Lilly and Company Inc, Indianapolis, USA.